Ch.3 Q.#15 Why can an organ be permanently damaged if its cells are amitotic?

When cell groups become amitotic, they almost completely lose their abilities to divide when they are fully mature. To become amitotic, there must be cell division by simple cleavage of the nucleus and division of the cytoplasm without spindle formation or appearance of chromosomes. Cells that are amitotic wouldn't be able to heal or repair itself. This would also explain why the heart of an individual who had multiple heart attacks become weaker. If cells are amitotic, an organ is permanently damaged because damaged area cannot be repaired by the division of remaining cells to replace the cells that are lost.